title
summary
CID
type
category
tags
status
slug
date
password
icon
📇 文献索引
THE MEDICAL MANAGEMENT OF FIBRODYSPLASIA OSSIFICANS PROGRESSIVA: CURRENT TREATMENT CONSIDERATIONS
Post
指南
推荐
必看精选
热门文章
实用指导
ICC
Published
icc-fop-guidance
Dec 17, 2023
Molecular Developmental Biology of Fibrodysplasia Ossificans Progressiva: Measuring the Giant by Its Toe
272103968
Post
综述
Invisible
Molecular-Developmental-Biology-of-FOP
Oct 26, 2024
大会讨论热点之一是今年最新发现的控制靶点MMP-9，MMP-9的发现标志着FOP以及其他疾病导致的异位骨化，又新增了一个控制靶点，实验室数据说明此靶点对于控制异位骨化极其有效。
Post
Published
2024-FOP-Summit
Oct 16, 2024
卡普兰教授提到了这位同时带有 FOP 经典点位 R206 突变及 MMP-9 相关基因点突变的患者。 笔者在大会现场见到该病人，目测该病人全身主要关节活动正常，仅仅在颈背部略有一些僵 硬感，其它活动与常人无明显异常。
Post
Published
2024-FOP-XiaowenPapa-noted
Oct 16, 2024
International physician survey on management of FOP: a modified Delphi study
4359840
Post
研究
推荐
热门文章
ICC
Published
4359840
Dec 24, 2023
Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP)
52916494
Post
研究
推荐
必看精选
ICC
Published
52916494
Dec 24, 2023
Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons.
3995352
Post
研究
ICC
Published
3995352
Oct 6, 2024
ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages.
236450948
Post
研究
ICC
Invisible
236450948
Oct 27, 2024
Extra-articular ankylosis in fibrodysplasia ossificans progressiva.
39354067
Post
研究
ICC
Invisible
39354067
Oct 27, 2024
Fibrodysplasia ossificans progressiva: Clinical course, genetic mutations and genotype-phenotype correlations.
13118947
Post
研究
ICC
Invisible
13118947
Oct 5, 2024
Fibrodysplasia Ossificans Progressiva and Pregnancy: A Case Series and Review of the Literature.
252364699
Post
研究
ICC
Invisible
252364699
Oct 28, 2024
Limb swelling in patients who have fibrodysplasia ossificans progressiva.
1290880
Post
研究
ICC
Invisible
1290880
Oct 28, 2024
Preventing pressure ulcers: a systemic review.
263503856
Post
研究
ICC
Invisible
263503856
Oct 28, 2024
Review of the Current Management of Pressure Ulcers
31927177
Post
研究
ICC
Invisible
31927177
Oct 28, 2024
Fibrodysplasia ossificans progressive presenting as fibrous scalp nodules.
35619923
Post
研究
ICC
Invisible
35619923
Oct 28, 2024
A viable pregnancy in a patient with myositis ossificans progressiva
25791914
Post
研究
ICC
Invisible
25791914
Oct 28, 2024
Current challenges and opportunities in the care of patients with fibrodysplasia ossificans progressiva (FOP): an international, multi-stakeholder perspective
248220058
Post
研究
ICC
Invisible
248220058
Oct 28, 2024
The impact of fibrodysplasia ossificans progressiva (FOP) on patients and their family members: results from an international burden of illness survey
251843500
Post
研究
ICC
Invisible
251843500
Oct 28, 2024
Mutation analysis and prenatal Exclusion of Fibrodysplasia Ossificans Progressiva in a Chinese fetus.
41366203
Post
研究
ICC
Invisible
41366203
Oct 28, 2024
Pregnancy in fibrodysplasia ossificans progressiva.
20609609
Post
研究
ICC
Invisible
20609609
Oct 28, 2024
Surgical and Radiological Management of Complicated Uterine Leiomyoma Aided by 3D Models in a Patient with Fibrodysplasia Ossificans Progressiva
235394624
Post
研究
ICC
Invisible
235394624
Oct 28, 2024
Myositis ossificans progressiva and pregnancy.
46224880
Post
研究
ICC
Invisible
46224880
Oct 28, 2024
Dental care for patients who are unable to open their mouths.
29531593
Post
研究
ICC
Invisible
29531593
Oct 28, 2024
A US population‐based study of uterine fibroid diagnosis incidence, trends, and prevalence: 2005 through 2014
52931240
Post
研究
ICC
Invisible
52931240
Oct 28, 2024
Personal oral hygiene and dental caries: A systematic review of randomised controlled trials
21697327
Post
研究
ICC
Invisible
21697327
Oct 28, 2024
Managing Carious Lesions: Consensus Recommendations on Terminology
10553555
Post
研究
ICC
Invisible
10553555
Oct 28, 2024
Limitations of Jaw Movement in Fibrodysplasia Ossificans Progressiva: A Review
247749499
Post
研究
ICC
Invisible
247749499
Oct 28, 2024
Clinical trials of silver diamine fluoride in arresting caries among children: A Systematic Review.
30931743
Post
研究
ICC
Invisible
30931743
Oct 28, 2024
In vitro remineralization associated with a bioerodible fluoridated resin and a fluoride varnish
27985960
Post
研究
ICC
Invisible
27985960
Oct 28, 2024
Oral management in a patient with fibrodysplasia ossificans progressiva
27419587
Post
研究
ICC
Invisible
27419587
Oct 28, 2024
Abnormal temporomandibular joints in fibrodysplasia ossificans progressiva
39897660
Post
研究
ICC
Invisible
39897660
Oct 28, 2024
White Paper on Dental Caries Prevention and Management: A summary of the current evidence and the key issues in controlling this preventable disease
30154531
Post
研究
ICC
Invisible
30154531
Oct 28, 2024
Flare-Up After Maxillofacial Surgery in a Patient with Fibrodysplasia Ossificans Progressiva: An [18F]-NaF PET/CT Study and a Systematic Review
30283890
Post
研究
ICC
Invisible
30283890
Oct 27, 2024
Anaesthesia management of child with fibrodysplasia ossificans progressiva.
25606084
Post
研究
ICC
Invisible
25606084
Oct 28, 2024
Dental Caries: An update on dental trends and therapy.
44284773
Post
研究
ICC
Invisible
44284773
Oct 28, 2024
Evidence-based clinical practice guideline on restorative treatments for caries lesions: A report from the American Dental Association.
259286761
Post
研究
ICC
Invisible
259286761
Oct 28, 2024
Fibrodysplasia ossificans progressiva: report of a case with guidelines for pediatric dental and anesthetic management
42494814
Post
研究
ICC
Invisible
42494814
Oct 27, 2024
Oral and dental healthcare and anesthesia for persons with fibrodysplasia ossificans progressiva.
73391107
Post
研究
ICC
Invisible
73391107
Oct 27, 2024
Submandibular space swelling in a patient with fibrodysplasia ossificans progressiva: a diagnostic dilemma
38195825
Post
研究
ICC
Invisible
38195825
Oct 27, 2024
Low body mass index: a risk factor for superior mesenteric artery syndrome in adolescents undergoing spinal fusion for scoliosis.
25368547
Post
研究
ICC
Invisible
25368547
Oct 27, 2024
Pulmonary and cardiac function in advanced fibrodysplasia ossificans progressiva.
46340285
Post
研究
ICC
Invisible
46340285
Oct 27, 2024
Craniofacial findings in fibrodysplasia ossificans progressiva: computerized tomography evaluation.
205495053
Post
研究
ICC
Invisible
205495053
Oct 27, 2024
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
11863338
Post
研究
ICC
Invisible
11863338
Oct 27, 2024
Thoracic insufficiency syndrome in patients with fibrodysplasia ossificans progressiva.
71725732
Post
研究
ICC
Invisible
71725732
Oct 27, 2024
Respiratory failure in disorders of the thoracic cage.
26491866
Post
研究
ICC
Invisible
26491866
Oct 27, 2024
Dietary reference intakes for calcium and vitamin D.
27351419
Post
研究
ICC
Invisible
27351419
Oct 27, 2024
General anesthesia for dental procedures in patients with fibrodysplasia ossificans progressiva: A review of 42 cases in 30 patients.
26696512
Post
研究
ICC
Invisible
26696512
Oct 27, 2024
Patients with ACVR1(R206H) mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of fibrodysplasia ossificans progressiva
220843878
Post
研究
ICC
Invisible
220843878
Oct 27, 2024
The FOP connection registry: Design of an international patient-sponsored registry for Fibrodysplasia Ossificans Progressiva.
4189451
Post
研究
ICC
Invisible
4189451
Oct 27, 2024
Spinal deformity in patients who have FOP.
7929490
Post
研究
ICC
Invisible
7929490
Oct 27, 2024
Chin-on-chest deformity in patients who have fibrodysplasia ossificans progressiva (FOP).
207281428
Post
研究
ICC
Invisible
207281428
Oct 27, 2024
Scalp nodules as a presenting sign of fibrodysplasia ossificans progressiva: a register-based study
24269486
Post
研究
ICC
Invisible
24269486
Oct 27, 2024
Prevalence and risk factors for kidney stones in fibrodysplasia ossificans progressiva.
4205222
Post
研究
ICC
Invisible
4205222
Oct 27, 2024
Mobility challenges and solutions for fibrodysplasia ossificans progressiva
3256982
Post
研究
ICC
Invisible
3256982
Oct 27, 2024
Fibrodysplasia Ossificans Progressiva in a Four year Old Child
16993247
Post
研究
ICC
Invisible
16993247
Oct 27, 2024
Rehabilitation for individuals with fibrodysplasia ossificans progressiva.
71657940
Post
研究
ICC
Invisible
71657940
Oct 27, 2024
The role of mast cells in functional GI disorders
3456082
Post
研究
ICC
Invisible
3456082
Oct 27, 2024
Superior mesenteric artery syndrome in a patient with fibrodysplasia ossificans progressiva.
260034286
Post
研究
ICC
Invisible
260034286
Oct 27, 2024
General anesthesia in fibrodysplasia ossificans progressiva: a case report and clinical review.
2901001
Post
研究
ICC
Invisible
2901001
Oct 27, 2024
Conductive hearing loss in individuals with fibrodysplasia ossificans progressive.
42582268
Post
研究
ICC
Invisible
42582268
Oct 27, 2024
Catastrophic falls in patients who have fibrodysplasia ossificans progressiva.
36879069
Post
研究
ICC
Invisible
36879069
Oct 27, 2024
Severe restriction in jaw movement after route injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva.
24480464
Post
研究
ICC
Invisible
24480464
Oct 27, 2024
Fibrodysplasia ossificans progressiva with two emergency laparotomies: A case report.
220700849
Post
研究
ICC
Invisible
220700849
Oct 27, 2024
The diversity of the clinical phenotypes in patients with fibrodysplasia ossificans progressiva.
6302431
Post
研究
ICC
Invisible
6302431
Oct 27, 2024
Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)
255323464
Post
研究
ICC
Invisible
255323464
Oct 27, 2024
Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva.
30588134
Post
研究
ICC
Invisible
30588134
Oct 27, 2024
Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial
263225722
Post
研究
ICC
Invisible
263225722
Oct 27, 2024
Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, PlaceboControlled, Double-Blind Phase 2 Trial.
250697248
Post
研究
ICC
Invisible
250697248
Oct 27, 2024
Druggable targets, clinical trial design and proposed pharmacological management in fibrodysplasia ossificans progressiva.
216317189
Post
研究
ICC
Invisible
216317189
Oct 27, 2024
Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery
252973282
Post
研究
ICC
Invisible
252973282
Oct 27, 2024
Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva.
226228593
Post
研究
ICC
Invisible
226228593
Oct 27, 2024
Clearance of Senescent Cells from Injured Muscle Abrogates Heterotopic Ossification in Mouse Models of Fibrodysplasia Ossificans Progressiva.
219904645
Post
研究
ICC
Invisible
219904645
Oct 27, 2024
Therapeutic advances for blocking heterotopic ossification in fibrodysplasia ossificans progressiva.
54489374
Post
研究
ICC
Invisible
54489374
Oct 27, 2024
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists.
18025397
Post
研究
ICC
Invisible
18025397
Oct 27, 2024
Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1.
218859465
Post
研究
ICC
Invisible
218859465
Oct 27, 2024
Pharmacokinetics and pharmacodynamics of Garetosmab (Anti-Activin A): Results from a first-in-human phase 1 study.
219904645
Post
研究
ICC
Invisible
219904645
Oct 27, 2024
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice.
236436962
Post
研究
ICC
Invisible
236436962
Oct 27, 2024
Restoration of normal BMP signaling levels and osteogenic differentiation in FOP mesenchymal progenitor cells by mutant allele–specific targeting.
9951856
Post
研究
ICC
Invisible
9951856
Oct 27, 2024
Derailing heterotopic ossification and RARing to go.
205377984
Post
研究
ICC
Invisible
205377984
Oct 27, 2024
A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders
258908782
Post
研究
ICC
Invisible
258908782
Oct 27, 2024
Application of small molecules BMP inhibitors in physiology and disease.
31596274
Post
研究
ICC
Invisible
31596274
Oct 27, 2024
Twenty-Ninth Annual Report of the fibrodysplasia ossificans progressiva (FOP) collaborative research project.
Post
研究
ICC
Invisible
Twenty-Ninth-Annual-Report-fop
Oct 27, 2024
Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.
919276
Post
研究
ICC
Invisible
919276
Oct 27, 2024
Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles
248504401
Post
研究
ICC
Invisible
248504401
Oct 27, 2024
The twilight zone: benefit, risk & hope in clinical trials for FOP.
Post
研究
ICC
Invisible
The-twilight-zone
Oct 27, 2024
Evolving data about subtrochanteric fractures and bisphosphonates
20335574
Post
研究
ICC
Invisible
20335574
Oct 27, 2024
Effect of warfarin sodium therapy on excretion of 4-carboxy-L-glutamic acid in scleroderma, dermatomyositis, and myositis ossificans progressiva.
29086608
Post
研究
ICC
Invisible
29086608
Oct 27, 2024
Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
236162816
Post
研究
ICC
Invisible
236162816
Oct 27, 2024
Rosiglitazone therapy is associated with major clinical improvements in a patient with fibrodysplasia ossificans progressiva
19929438
Post
研究
ICC
Invisible
19929438
Oct 27, 2024
Long term use of interleukin-1 inhibitors reduce flare activity in patients with fibrodysplasia ossificans progressiva
269723907
Post
研究
ICC
Invisible
269723907
Oct 27, 2024
Is there a biological basis for treatment of fibrodysplasia ossificans progressiva with rosiglitazone? Potential benefits and undesired effects.
20613955
Post
研究
ICC
Invisible
20613955
Oct 27, 2024
Treatment considerations for the management of fibrodysplasia ossificans progressiva
56592833
Post
研究
ICC
Invisible
56592833
Oct 27, 2024
Optimal treatment of fibrodysplasia ossificans progressiva with surgical excision of heterotopic bone, indomethacin, and irradiation
35138014
Post
研究
ICC
Invisible
35138014
Oct 27, 2024
Pacritinib is a potent ACVR1 inhibitor with significant anemia benefit in patients with myelofibrosis
37552106
Post
研究
ICC
Invisible
37552106
Oct 27, 2024
Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification
4582688
Post
研究
ICC
Invisible
4582688
Oct 27, 2024
Long-term safety and effectiveness of canakinumab therapy in patients with cryopyrin-associated periodic syndrome: results from the β-Confident Registry
34001647
Post
研究
ICC
Invisible
34001647
Oct 27, 2024
ACVR1/JAK1/JAK2 inhibitor momelotinib reverses transfusion dependency and suppresses hepcidin in myelofibrosis phase 2 trial
32915978
Post
研究
ICC
Invisible
32915978
Oct 27, 2024
Successful experience of tofacitinib treatment in patients with Fibrodysplasia Ossificans Progressiva
37644581
Post
研究
ICC
Invisible
37644581
Oct 27, 2024
ACVR1 R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages.
236450948
Post
研究
ICC
Invisible
236450948
Oct 27, 2024
Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines
10803515
Post
研究
ICC
Invisible
10803515
Oct 27, 2024
Paradoxical side effects of bisphosphonates on the skeleton: What do we know and what can we do?
29323712
Post
研究
ICC
Invisible
29323712
Oct 27, 2024
Is fibrodysplasia ossificans progressiva an interleukin-1 driven auto-inflammatory syndrome?
31864380
Post
研究
ICC
Invisible
31864380
Oct 27, 2024
Mast Cells and KIT as Potential Therapeutic Targets in Severe Asthma
28514622
Post
研究
ICC
Invisible
28514622
Oct 27, 2024
Children and the risk of fractures caused by oral corticosteroids
6649063
Post
研究
ICC
Invisible
6649063
Oct 27, 2024
Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation
18619615
Post
研究
ICC
Invisible
18619615
Oct 27, 2024
Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid
12183663
Post
研究
ICC
Invisible
12183663
Oct 27, 2024
Bisphosphonate-induced osteopetrosis
12890844
Post
研究
ICC
Invisible
12890844
Oct 27, 2024
Variant BMP receptor mutations causing fibrodysplasia ossificans progressiva (FOP) in humans show BMP ligand-independent receptor activation in zebrafish.
4320030
Post
研究
ICC
Invisible
4320030
Oct 27, 2024
Amino-bisphosphonates in heterotopic ossification: first experience in five consecutive cases
15867938
Post
研究
ICC
Invisible
15867938
Oct 27, 2024
Bisphosphonates, a new treatment for glucocorticoid-induced osteoporosis in children.
12793604
Post
研究
ICC
Invisible
12793604
Oct 27, 2024
Bone mass, size, and density in children and adolescents with osteogenesis imperfecta: effect of intravenous pamidronate therapy
12674321
Post
研究
ICC
Invisible
12674321
Oct 27, 2024
Pamidronate induces modifications of circulating angiogenetic factors in cancer patients
12006522
Post
研究
ICC
Invisible
12006522
Oct 27, 2024
Severe hypocalcemia after intravenous bisphosphonate therapy in occult vitamin D deficiency
12686715
Post
研究
ICC
Invisible
12686715
Oct 27, 2024
The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta
12417568
Post
研究
ICC
Invisible
12417568
Oct 27, 2024
Bisphosphonates in bone disease other than osteoporosis
11858352
Post
研究
ICC
Invisible
11858352
Oct 27, 2024
Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways.
45522727
Post
研究
ICC
Invisible
45522727
Oct 27, 2024
Intravenous bisphosphonate therapy in children with osteogenesis imperfecta.
22472978
Post
研究
ICC
Invisible
22472978
Oct 27, 2024
Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro
3174485
Post
研究
ICC
Invisible
3174485
Oct 27, 2024
Role of osteoclasts in heterotopic ossification enhanced by fibrodysplasia ossificans progressiva-related activin-like kinase 2 mutation in mice.
42100250
Post
研究
ICC
Invisible
42100250
Oct 27, 2024
Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of The American Society for Bone and Mineral Research
17663640
Post
研究
ICC
Invisible
17663640
Oct 27, 2024
Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification
13402840
Post
研究
ICC
Invisible
13402840
Oct 27, 2024
Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva.
235126326
Post
研究
ICC
Invisible
235126326
Oct 27, 2024
Two-year clinical trial of oral alendronate versus intravenous pamidronate in children with osteogenesis imperfecta.
12996685
Post
研究
ICC
Invisible
12996685
Oct 27, 2024
Short-term safety of zoledronic acid in young patients with bone disorders: an extensive institutional experience.
23318639
Post
研究
ICC
Invisible
23318639
Oct 27, 2024
Antiresorptive therapies for osteoporosis: a clinical overview.
19636249
Post
研究
ICC
Invisible
19636249
Oct 27, 2024
Osteonecrosis of the jaw--do bisphosphonates pose a risk?
26902052
Post
研究
ICC
Invisible
26902052
Oct 27, 2024
Effects of intravenous etidronate and oral corticosteroids in fibrodysplasia ossificans progressiva.
44538694
Post
研究
ICC
Invisible
44538694
Oct 27, 2024
Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur
5050583
Post
研究
ICC
Invisible
5050583
Oct 27, 2024
Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases.
4215169
Post
研究
ICC
Invisible
4215169
Oct 27, 2024
Use of imatinib in the prevention of heterotopic ossification.
10623058
Post
研究
ICC
Invisible
10623058
Oct 27, 2024
Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib
26065005
Post
研究
ICC
Invisible
26065005
Oct 27, 2024
Non-steroidal anti-inflammatory drugs for heterotopic ossification prophylaxis after total hip arthroplasty.
29954195
Post
研究
ICC
Invisible
29954195
Oct 27, 2024
Clinical practice. Chronic urticaria and angioedema.
6437015
Post
研究
ICC
Invisible
6437015
Oct 27, 2024
Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP)
4203040
Post
研究
ICC
Invisible
4203040
Oct 27, 2024
KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma.
205101177
Post
研究
ICC
Invisible
205101177
Oct 27, 2024
The role of prostaglandins in bone formation
46445120
Post
研究
ICC
Invisible
46445120
Oct 27, 2024
Comparison of ketoprofen, piroxicam, and diclofenac gels in the treatment of acute soft-tissue injury in general practice. General Practice Study Group.
1000680
Post
研究
ICC
Invisible
1000680
Oct 27, 2024
Pain management therapy: the benefits of compounded transdermal pain medication.
4503403
Post
研究
ICC
Invisible
4503403
Oct 27, 2024
Compounded pain formulations: what is the evidence?
23136005
Post
研究
ICC
Invisible
23136005
Oct 27, 2024
Comparison of thromboembolic events in patients treated with celecoxib, a cyclooxygenase-2 specific inhibitor, versus ibuprofen or diclofenac
24964566
Post
研究
ICC
Invisible
24964566
Oct 27, 2024
Systemic administration of an anabolic dose of PGE2 in young rats increases the osteogenic capacity of bone marrow.
40517481
Post
研究
ICC
Invisible
40517481
Oct 27, 2024
Clinical experience with cyclooxygenase-2 inhibitors
6628263
Post
研究
ICC
Invisible
6628263
Oct 27, 2024
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing
32304338
Post
研究
ICC
Invisible
32304338
Oct 27, 2024
Safety of celecoxib and nonselective nonsteroidal anti-inflammatory drugs in juvenile idiopathic arthritis: results of the phase 4 registry.
8693053
Post
研究
ICC
Invisible
8693053
Oct 27, 2024
Single-dose and steady-state pharmacokinetics of celecoxib in children
41841597
Post
研究
ICC
Invisible
41841597
Oct 27, 2024
Failing the public health-rofecoxib, Merck, and the FDA.
12516952
Post
研究
ICC
Invisible
12516952
Oct 27, 2024
Cyclooxygenase-2: its rich diversity of roles and possible application of its selective inhibitors
19917790
Post
研究
ICC
Invisible
19917790
Oct 27, 2024
COX-2: where are we in 2003? Be strong and resolute: continue to use COX-2 selective inhibitors at recommended dosages in appropriate patients.
9004453
Post
研究
ICC
Invisible
9004453
Oct 27, 2024
Effects of indomethacin on demineralized boneinduced heterotopic ossification in the rat.
39592393
Post
研究
ICC
Invisible
39592393
Oct 27, 2024
Glucocorticoid-independent modulation of GF activity: Implications for immunotherapy.
8926548
Post
研究
ICC
Invisible
8926548
Oct 27, 2024
Inherited human diseases of heterotopic bone formation.
25205044
Post
研究
ICC
Invisible
25205044
Oct 27, 2024
Gastrointestinal safety of etoricoxib in osteoarthritis and rheumatoid arthritis: A meta-analysis.
4537101
Post
研究
ICC
Invisible
4537101
Oct 27, 2024
Efficacy, tolerability, and upper gastrointestinal safety of celecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomized controlled trials.
19024236
Post
研究
ICC
Invisible
19024236
Oct 27, 2024
The cardiovascular pharmacology of non-steroidal anti-inflammatory drugs.
28651847
Post
研究
ICC
Invisible
28651847
Oct 27, 2024
The immunological contribution to heterotopic ossification disorders.
207336453
Post
研究
ICC
Invisible
207336453
Oct 27, 2024
Is etoricoxib effective in preventing heterotopic ossification after primary total hip arthroplasty?
23186604
Post
研究
ICC
Invisible
23186604
Oct 27, 2024
Children and the risk of fractures caused by oral corticosteroids.
6649063
Post
研究
ICC
Invisible
6649063
Oct 27, 2024
BMP type I receptor inhibition reduces heterotopic ossification.
5437265
Post
研究
ICC
Invisible
5437265
Oct 27, 2024
Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 Pathway.
72403723
Post
研究
ICC
Invisible
72403723
Oct 27, 2024
Submandibular swelling in patients with fibrodysplasia ossificans progressiva.
20061436
Post
研究
ICC
Invisible
20061436
Oct 27, 2024
Anti-inflammatory action of glucocorticoids – new mechanisms for old drugs.
5744727
Post
研究
ICC
Invisible
5744727
Oct 27, 2024
One hormone two actions: anti and pro-inflammatory effects of glucocorticoids.
13784613
Post
研究
ICC
Invisible
13784613
Oct 27, 2024
Clinical staging of fibrodysplasia ossificans progressiva
4217166
Post
研究
ICC
Invisible
4217166
Oct 27, 2024
Hard targets for a second skeleton: therapeutic horizons for fibrodysplasia ossificans progressiva (FOP).
27810716
Post
研究
ICC
Invisible
27810716
Oct 27, 2024
A contribution to the study of myositis ossificans progressiva.
42120969
Post
研究
ICC
Invisible
42120969
Oct 27, 2024
The key to the closet is the key to the kingdom: a common lesson of rare diseases.
Post
研究
ICC
Invisible
none-The key to the closet
Oct 27, 2024
An adult zebrafish model of fibrodysplasia ossificans progressiva.
53249289
Post
研究
ICC
Invisible
53249289
Oct 27, 2024
Drosophila models of FOP provide mechanistic insight.
1356058
Post
研究
ICC
Invisible
1356058
Oct 27, 2024
Hyperactive BMP signaling induced by ALK2 (R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva.
10405036
Post
研究
ICC
Invisible
10405036
Oct 27, 2024
Activin A amplifies dysregulated BMP signaling and induces chondro-osseous differentiation of primary connective tissue progenitor cells in patients with fibrodysplasia ossificans progressiva (FOP).
4295471
Post
研究
ICC
Invisible
4295471
Oct 26, 2024
Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis.
2231886
Post
研究
ICC
Invisible
2231886
Oct 27, 2024
Animal models of fibrodysplasia ossificans progressiva.
21546600
Post
研究
ICC
Invisible
21546600
Oct 27, 2024
Identification of the identical human mutation in ACVR1 in two cats with fibrodysplasia ossificans progressiva.
128353855
Post
研究
ICC
Invisible
128353855
Oct 27, 2024
Palovarotene inhibits heterotopic ossification and maintains limb mobility and growth in mice with the human ACVR1 (R206H) fibrodysplasia ossificans progressiva (FOP) mutation.
5475982
Post
研究
ICC
Invisible
5475982
Oct 27, 2024
BMP signaling and skeletal development in fibrodysplasia ossificans progressiva (FOP)
235448862
Post
研究
ICC
Invisible
235448862
Oct 26, 2024
Heterotopic ossification in mouse models of fibrodysplasia ossificans progressiva
53249142
Post
研究
ICC
Invisible
53249142
Oct 27, 2024
Genetic transmission of fibrodysplasia ossificans progressiva. Report of a family.
42164620
Post
研究
ICC
Invisible
42164620
Oct 27, 2024
Early diagnosis of fibrodysplasia ossificans progressiva.
22466755
Post
研究
ICC
Invisible
22466755
Oct 27, 2024
Paternal age effect in fibrodysplasia ossificans progressiva.
20588898
Post
研究
ICC
Invisible
20588898
Oct 27, 2024
Prevalence of fibrodysplasia ossificans progressiva (FOP) in the United States: estimate from three treatment centers and a patient organization.
236921073
Post
研究
ICC
Invisible
236921073
Oct 27, 2024
The genetics of fibrodysplasia ossificans progressiva.
84605282
Post
研究
ICC
Invisible
84605282
Oct 27, 2024
Matrix metalloproteinase-9 deficiency confers resilience in fibrodysplasia ossificans progressiva in a man and mice
267744486
Post
研究
ICC
Invisible
267744486
Oct 27, 2024
Inflammation in Fibrodysplasia Ossificans Progressiva and Other Forms of Heterotopic Ossification
207936284
Post
研究
ICC
Invisible
207936284
Oct 27, 2024
Fibrodysplasia ossificans progressiva in Spain: epidemiological, clinical, and genetic aspects.
37529869
Post
研究
ICC
Invisible
37529869
Oct 27, 2024
Three pairs of monozygotic twins with fibrodysplasia ossificans progressiva: the role of environment in the progression of heterotopic ossification.
57554151
Post
研究
ICC
Invisible
57554151
Oct 27, 2024
Deterioration of pulmonary function: An early complication in Fibrodysplasia Ossificans Progressiva.
232293598
Post
研究
ICC
Invisible
232293598
Oct 6, 2024
Inherited human disease of heterotopic bone formation.
25205044
Post
研究
ICC
Invisible
25205044
Oct 6, 2024
Plasma‐Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States
245504485
Post
研究
ICC
Invisible
245504485
Oct 27, 2024
Prevalence of fibrodysplasia ossificans progressiva (FOP) in France: an estimate based on a record linkage of two national databases
9213696
Post
研究
ICC
Invisible
9213696
Oct 27, 2024
The phenotype of fibrodysplasia ossificans progressiva.
71339634
Post
研究
ICC
Invisible
71339634
Oct 6, 2024
ECSIT links TLR and BMP signaling in FOP connective tissue progenitor cells
206286371
Post
研究
ICC
Invisible
206286371
Oct 27, 2024
Genetic aspects of fibrodysplasia ossificans progressiva.
17439095
Post
研究
ICC
Invisible
17439095
Oct 27, 2024
Cellular hypoxia promotes heterotopic ossification by amplifying BMP signaling.
33020658
Post
研究
ICC
Invisible
33020658
Oct 27, 2024
An ACVR1R375P pathogenic variant in two families with mild fibrodysplasia ossificans progressiva
244800471
Post
研究
ICC
Invisible
244800471
Oct 27, 2024
Actionable disease insights from bedside-to-bench investigation in fibrodysplasia ossificans progressiva.
269292215
Post
研究
ICC
Invisible
269292215
Oct 27, 2024
A cumulative analogue joint involvement scale (CAJIS) for fibrodysplasia ossificans progressiva (FOP).
4053040
Post
研究
ICC
Invisible
4053040
Oct 6, 2024
Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva.
45511250
Post
研究
ICC
Invisible
45511250
Oct 6, 2024
Granting immunity to FOP and catching heterotopic ossification in the Act.
205153910
Post
研究
ICC
Invisible
205153910
Oct 27, 2024
Mast cell involvement in fibrodysplasia ossificans progressiva (FOP).
22897027
Post
研究
ICC
Invisible
22897027
Oct 7, 2024
Modeling the ACVR1 R206H mutation in human skeletal muscle stem cells.
243940371
Post
研究
ICC
Invisible
243940371
Oct 7, 2024
Multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva (ACVR1c.772G>A; R258G): a report of two patients
26971105
Post
研究
ICC
Invisible
26971105
Oct 26, 2024
NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification
53442112
Post
研究
ICC
Invisible
53442112
Oct 26, 2024
An Acvr1 Knock-in mouse has fibrodysplasia ossificans progressiva.
34484544
Post
研究
ICC
Invisible
34484544
Oct 7, 2024
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
14118736
Post
研究
ICC
Invisible
14118736
Oct 7, 2024
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP‐induced osteoblast differentiation and bone formation
207269687
Post
研究
ICC
Invisible
ALK2-R206H-mutation-linked
Oct 7, 2024
Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva.
39487901
Post
研究
ICC
Invisible
Acute-lymphocytic-infiltration
Oct 7, 2024
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
41579747
Post
研究
ICC
Invisible
41579747
Oct 7, 2024
Dynamics of skeletal muscle-resident stem cells during myogenesis in fibrodysplasia ossificans progressiva
245936653
Post
研究
ICC
Invisible
Dynamics-of-skeletal muscle-resident
Oct 7, 2024
Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish.
221540720
Post
研究
ICC
Invisible
221540720
Oct 7, 2024
Elevated BMP and Mechanical Signaling Through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis
159039771
Post
研究
ICC
Invisible
Elevated-BMP-and-Mechanical-Signaling
Oct 7, 2024
Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).
24767611
Post
研究
ICC
Invisible
Dysregulated-BMP-signaling
Oct 7, 2024
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva.
25407404
Post
研究
ICC
Invisible
Structure-of-the-bone-morphogenetic
Oct 7, 2024
Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral bone ossification (HEO) in fibrodysplasia ossification progressiva (FOP).
4147494
Post
研究
ICC
Invisible
Cartilage-derived-retinoic
Oct 7, 2024
ACVR1(R206H) receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.
34831835
Post
研究
ICC
Invisible
34831835
Oct 7, 2024
Variable signaling activity by FOP ACVR1 mutations.
4348282
Post
研究
ICC
Invisible
4348282
Oct 7, 2024
Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.
12329263
Post
研究
ICC
Published
12329263
Oct 7, 2024
The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling.
12436217
Post
研究
ICC
Invisible
The-FOP-metamorphogene-encodes
Oct 7, 2024
Pathogenic ACVR1 R206H activation by Activin A-induced receptor clustering and autophosphorylation.
234769488
Post
研究
ICC
Invisible
Pathogenic-ACVR1-R206H
Oct 7, 2024
Fibrodysplasia ossificans progressiva: A clue from the fly?
26642757
Post
研究
ICC
Invisible
26642757
Oct 7, 2024
ACVR1 R206H FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification.
53198741
Post
研究
ICC
Invisible
ACVR1-R206H-FOP-mutation-alters
Oct 7, 2024
In vitro analysis of dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP.
32990783
Post
研究
ICC
Invisible
In-vitro-analysis-of-dysregulated
Oct 7, 2024
Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification.
21519639
Post
研究
ICC
Invisible
Alk2-regulates-early-chondrogenic
Oct 7, 2024
Reduced GS Domain Serine/Threonine Requirements of Fibrodysplasia Ossificans Progressiva Mutant Type I BMP Receptor ACVR1 in the Zebrafish.
254181810
Post
研究
ICC
Invisible
254181810
Oct 7, 2024
Functional modeling of the ACVR1 (R206H) mutation in FOP.
11493870
Post
研究
ICC
Invisible
Functional-modeling-of-the-ACVR1
Oct 7, 2024
Plasma‐Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States
245504485
Post
研究
ICC
Invisible
Plasma‐Soluble-Biomarkers
Oct 7, 2024
Urinary basic fibroblast growth factor: a biochemical marker for preosseous fibroproliferative lesions in patients with FOP.
35739793
Post
研究
ICC
Invisible
Urinary-basic-fibroblast
Oct 7, 2024
Hematopoietic stem cell contribution to ectopic skeletogenesis.
33411836
Post
研究
ICC
Invisible
33411836
Oct 7, 2024
The histopathology of fibrodysplasia ossificans progressiva: an endochondral process.
28979008
Post
研究
ICC
Invisible
an-endochondral-process.
Oct 7, 2024
Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.
45414950
Post
研究
ICC
Invisible
45414950
Oct 7, 2024
Fibrodysplasia ossificans progressiva: a current review of imaging findings.
24391905
Post
研究
ICC
Invisible
fop-a-current-review-of-imaging-findings
Oct 6, 2024
Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva.
34996704
Post
研究
ICC
Invisible
Proximal-tibial-osteochondromas
Oct 6, 2024
Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification.
25252314
Post
研究
ICC
Invisible
Multipotent-progenitors-resident
Oct 7, 2024
Depletion of Mast cells and macrophages impairs heterotopic ossification in an ACVR1 (R206H) mouse model of fibrodysplasia ossificans progressiva.
206009783
Post
研究
ICC
Invisible
206009783
Oct 7, 2024
The face signature of fibrodysplasia ossificans progressiva.
34532055
Post
研究
ICC
Invisible
34532055
Oct 6, 2024
The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study.
252497288
Post
研究
ICC
Invisible
252497288
Oct 6, 2024
Identification of progenitor cells that contribute to heterotopic skeletogenesis.
36703177
Post
研究
ICC
Invisible
Identification-of-progenitor-cells
Oct 7, 2024
The natural history of flare-ups in fibrodysplasia ossificans progressiva: a comprehensive global assessment.
45246651
Post
研究
ICC
Invisible
45246651
Oct 6, 2024
[18F]NaF PET/CT scan as an early marker of heterotopic ossification in fibrodysplasia ossificans progressiva.
4275682
Post
研究
ICC
Invisible
petct-scan-as-an-early-marker
Oct 6, 2024
Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva.
36163228
Post
研究
ICC
Invisible
Radiographic-and-scintigraphic-features
Oct 6, 2024
Fibrodysplasia ossificans progressiva（Mahboubi-2001）
Post
研究
ICC
Invisible
fop-Mahboubi-2001
Oct 6, 2024
Diagnostic value of magnetic resonance imaging in fibrodysplasia ossificans progressiva.
216383287
Post
研究
ICC
Invisible
Diagnostic-value-of-magnetic-resonance
Oct 6, 2024
Evolution of heterotopic bone in fibrodysplasia ossificans progressiva: An [(18)F]NaF PET/CT study.
75139126
Post
研究
ICC
Invisible
Evolution-of-heterotopic-bone
Oct 6, 2024
Imaging assessment in fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable.
4205900
Post
研究
ICC
Invisible
Imaging-assessment-in-fop
Oct 6, 2024
Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome.
26120266
Post
研究
ICC
Invisible
Developmental-anomalies-of-the-cervical-spine
Oct 6, 2024
Analog method for radiographic assessment of heterotopic bone in fibrodysplasia ossificans progressiva.
205234147
Post
研究
ICC
Invisible
analog-method-for-radiographic
Oct 6, 2024
Classical and atypical FOP phenotypes are caused by mutations in the BMP type I receptor ACVR1.
5312799
Post
研究
ICC
Invisible
5312799
Oct 6, 2024
Acute unilateral hip pain in fibrodysplasia ossificans progressiva.
4199172
Post
研究
ICC
Invisible
Acute-unilateral-hip-pain
Oct 6, 2024
Fibrodysplasia ossificans progressiva: a disorder of osteochondrogenesis.
220889037
Post
研究
ICC
Invisible
a-disorder-of-osteochondrogenesis
Oct 6, 2024
Fibrodysplasia ossificans progressiva (FOP): A segmental progeroid syndrome.
210117364
Post
研究
ICC
Invisible
210117364
Oct 6, 2024
Joint-specific risk of impaired function in fibrodysplasia ossificans progressiva (FOP).
206285871
Post
研究
ICC
Invisible
206285871
Oct 6, 2024
Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP).
227100557
Post
研究
ICC
Invisible
dysregulated-BMP-signaling-through-ACVR1
Oct 6, 2024
Lumbar puncture and surgical intervention in a child with undiagnosed fibrodysplasia ossificans progressiva.
7977125
Post
研究
ICC
Invisible
7977125
Oct 6, 2024
Spatial patterns of heterotopic ossification in fibrodysplasia ossificans progressiva correlate with anatomic temperature gradients.
233457903
Post
研究
ICC
Invisible
Spatial-patterns-of-heterotopic-ossification
Oct 6, 2024
The developmental phenotype of the great toe in fibrodysplasia ossificans progressiva.
227496905
Post
研究
ICC
Invisible
the-developmental-phenotype-of-the-great-toe
Oct 6, 2024
Age and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva.
30963376
Post
研究
ICC
Invisible
age-and joint-specific-risk
Oct 6, 2024
Skeletal malformations and developmental arthropathy in individuals who have fibrodysplasia ossificans progressiva.
204918443
Post
研究
ICC
Invisible
204918443
Oct 6, 2024
Self-reported baseline phenotypes from the international fibrodysplasia ossificans progressiva (FOP) association global registry.
211135392
Post
研究
ICC
Invisible
211135392
Oct 6, 2024
Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes.
145023793
Post
研究
ICC
Invisible
annotated-analysis-natural-history
Oct 6, 2024
Longitudinal patient-reported mobility assessment in fibrodysplasia ossificans progressiva (FOP).
4194733
Post
研究
ICC
Invisible
4194733
Oct 6, 2024
Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva.
389825
Post
研究
ICC
Invisible
389825
Oct 6, 2024
Compartment syndrome of the thigh in a patient with fibrodysplasia ossificans progressiva.
233866275
Post
研究
ICC
Invisible
compartment-syndrome-of-the-thigh
Oct 6, 2024
The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva.
43604055
Post
案例
ICC
Invisible
the-natural-history-of-heterotopic-ossification
Oct 6, 2024
Genetic disorders of heterotopic ossification: fibrodysplasia ossificans progressiva and progressive osseous heteroplasia
91863394
Post
研究
ICC
Invisible
fop_and_poh
Oct 6, 2024
Fibrodysplasia ossificans progressiva
11883047
Post
研究
ICC
Invisible
11883047
Oct 6, 2024
创立于2018年，最早由FOP患者明明，方方，大孔等小伙伴创立，最初希望通过QQ群汇聚分散在全国各地的FOP患者，经过大家的的努力，如今，国内已经找到100多位患者和家庭。
Post
珊瑚
Published
FOP_angel_coral
Dec 17, 2023